05229297 is referenced by 384 patents and cites 25 patents.

A cuvette and a method of use which prevent nucleic acid amplified by PCR technology from being released to the atmosphere, while still proceeding to a detection step to determine whether or not the nucleic acid is present. Detection reagents are either pre-incorporated into compartments in the cuvette or added after amplification. In the latter case, a check valve prevents amplified nucleic acid from being released. Transfer of liquids between compartments is achieved via the use of flexible compartment walls and an external pressure source, or via pistons that are part of the cuvette and operate on the compartments as a piston within a piston chamber.

Title
Containment cuvette for PCR and method of use
Application Number
306735
Publication Number
5229297
Application Date
October 15, 1992
Publication Date
July 20, 1993
Inventor
John B Findlay
Rochester
NY, US
William H Donish
Rochester
NY, US
Jeffrey A Wellman
Rochester
NY, US
Charles C Hinckley
Pittsford
NY, US
Leonard J Seaberg
Penfield
NY, US
Paul N Schnipelsky
Rochester
NY, US
Agent
Dana M Schmidt
Assignee
Eastman Kodak Company
NY, US
IPC
G01N 33/00
C12Q 1/68
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