05197977 is referenced by 348 patents and cites 9 patents.

A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.

Title
Drug delivery collagen-impregnated synthetic vascular graft
Application Number
575091
Publication Number
5197977
Application Date
April 30, 1992
Publication Date
March 30, 1993
Inventor
Milos Chvapil
Tucson
AZ, US
Kemal Schankereli
Stillwater
MN, US
Harmon Hoffman Jr
Wyckoff
NJ, US
Agent
Blum Kaplan
Assignee
Meadox Medicals
NJ, US
IPC
B61F 2/06
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