05190658 is referenced by 6 patents and cites 6 patents.

An apparatus and a method for size exclusion chromatography is provided. The apparatus is a chromatographic column adapted for use in size exclusion chromatography by having dimensions suitable for size exclusion chromatography and by having a packing material comprising generally spherical particles having wedge-shaped macropores. Preferred particles are in the shape of lamellar and/or acicular crystals extending radially outwardly from a central core region and comprise aluminum oxide, aluminum hydroxide or a mixture thereof. The method involves passing a solution of macromolecules through a column adapted for size exclusion chromatography packed with such particles. The particles effectively and efficiently separate a wide range of macromolecules in decreasing order of their molecular weight.

Title
Method for size exclusion chromatography
Application Number
7/830093
Publication Number
5190658
Application Date
February 3, 1992
Publication Date
March 2, 1993
Inventor
Christopher J Hardiman
St. Louis
MO, US
Jawed Asrar
Chesterfield
MO, US
Roger C Ayotte
Springfield
MA, US
Lev Z Vilenchik
Longmeadow
MA, US
Agent
Richard H Shear
Thomas E Kelley
Assignee
Monsanto Company
MO, US
IPC
B01D 15/08
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