05162990 is referenced by 49 patents.

The present invention is embodied in a method and algorithm for rapidly quantifying phagocytic functions using computer image analysis (CIA) of video light microscopic images. The method and algorithm involve sequential acquisition of bright field or phase contrast and epi-fluorescence video microscopic images of respective field, addition of the images, decision making, object referencing, morphological feature extraction, arithmetic operations, and statistical analysis. This invention provides significantly faster phagocytic functions analysis than manual microscopic examination and more detailed quantitative morphological data than flow cytometery.

Title
System and method for quantifying macrophage phagocytosis by computer image analysis
Application Number
7/540666
Publication Number
5162990
Application Date
June 15, 1990
Publication Date
November 10, 1992
Inventor
Gregory R Hook
Silver Spring
MD, US
Charles O Odeyale
Severn
MD, US
Agent
William C Garvert
A David Spevack
Assignee
The United States of America represented by the United States Navy
DC, US
IPC
G06F 15/42
G06F 15/00
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