05162525 is referenced by 123 patents and cites 2 patents.

Novel fluorogenic and chromogenic three-dimensional ionophores are provided which selectively bond ions such as potassium, sodium, and lithium, even in neutral aqueous or alcohol media. The novel ionophores comprse an "ion-recognizing system" fused to a "signal-moiety" through one or more heteroatoms having a non-bonded electron pair. The signal-moieties are selected from the group consisting of fused ring heterocyclics, fused aromatics, and substituted aromatics having at least one nitro or azo moiety. The ion-recognizing system is a three-dimensional cryptand. The ionophores are ideal for the selective and direct termination of ions in biological or environmental samples and the like.

Title
Fluorogenic and chromogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids
Application Number
7/80721
Publication Number
5162525
Application Date
July 31, 1987
Publication Date
November 10, 1992
Inventor
George S Hammond
Madison
NJ, US
Mariann E Lucas
Netcong
NJ, US
Davakaran Masilamani
Morristown
NJ, US
Agent
R C Stewart II
G H Fuchs
D L Webster
Assignee
Allied Signal
NJ, US
IPC
G01N 33/20
C07D 321/00
C07D 419/02
View Original Source