05141847 is referenced by 76 patents and cites 14 patents.

In an apparatus which applies periodic pulsation to a solution flowing through a conduit while undergoing perfusion by a pump, a first valve is disposed in the conduit downstream of the pump, a bypass line is provided to the conduit downstream of the first valve, and a second valve is disposed in the bypass line for withdrawing some of a first pulsed flow formed in the conduit by opening and closing the first valve, through the bypass line as a second pulsed flow. A valve driving circuit periodically opens and closes the first valve and second valve at predetermined time schedules so that the second pulsed flow is superimposed upon the first pulsed flow to form a waveform in the conduit. Any desired pulsatile waveform can be obtained by adjusting the pulse width, the crest values, the delay time, etc., of the two pulsed flows.

Title
Method and apparatus for producing pulsation
Application Number
7/482231
Publication Number
5141847
Application Date
February 20, 1990
Publication Date
August 25, 1992
Inventor
Atsushi Yoshihara
Tokyo
JP
Tetsuo Ikeda
Fukuoka
JP
Takashi Nishizaki
Fukuoka
JP
Kengo Fukuzawa
Ohita
JP
Mitsuo Shimada
Fukuoka
JP
Kenji Takenaka
Fukuoka
JP
Keizo Sugimachi
Fukuoka
JP
Agent
Rosen Dainow & Jacobs
Assignee
Kureha Chemical
JP
IPC
A01N 1/02
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