A peritoneal dialysis system is disclosed for administering substantially sterile dialysate to the peritoneal cavity of a patient. The system includes a dialyzer for passing a primary solution and a secondary solution therethrough to enabale removal of waste products from the primary solution to the secondary solution, and a primary circuit for selectively circulating a primary solution through the dialyzer. Connecting conduits or tubing is provided for selectively carrying primary solution from the primary circuit to the peritoneal cavity of the patient and for selectively withdrawing at least some of the solution from the peritoneal cavity back into the primary circuit. A pump is disposed in the primary circuit for causing primary solution to circulate in the primary circuit independently of transfer of primary solution between the primary circuit and the peritoneal cavity of the patient. A secondary circuit is coupled to the dialyzer for supplying a secondary solution thereto and for carrying secondary solution from the dialyzer. A supply source of primary solution is coupled to the primary circuit to initially charge the circuit, and a supply source of secondary solution is coupled to the secondary circuit to continually supply secondary solution thereto.