An apparatus for making surgical sutures in surgical operations, including a distal head part for making the sutures and receiving a cartridge containing staples and having a hollow punch, a control part at the other end and a flexible part transmitting to the distal head part control movements of the control part. The head part is detachable, and is not attached at the moment of insertion into the zone to be sutured. The head part is preferably replaced by a protective cap at the end of the flexible transmitting part. The protective cap allows easy insertion into an opening of a body part to be sutured. The cartridge is mounted to the head part in situ after the protective cap is removed and the head part is located in the zone in which the operation is to take place.