05112305 is referenced by 159 patents and cites 9 patents.

The present invention discloses a method of treatment of an atherosclerotic blood vessel. Specifically, therapeutic agents are delivered by means of a specialized catheter system to the deeper layers of the vessel wall with only minimal interuption of the vessel endothelium. This system will allow high local concentrations of otherwise toxic agents directly at the site of an atherosclerotic plaque. This invention will hopefully reduce the incidence of late restenosis attributed to cellular hyperplasia or rethrombosis.

Title
Catheter device for intramural delivery of therapeutic agents
Application Number
472898
Publication Number
5112305
Application Date
October 16, 1990
Publication Date
May 12, 1992
Inventor
Ferenc Denes
Budapest
HU
Peter Barath
West Hollywood
CA, US
Agent
Lyon & Lyon
Assignee
Cedars Sinai Medical Center
CA, US
IPC
A61M 29/00
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