05108438 is referenced by 296 patents and cites 26 patents.

A prosthetic intervertebral disc is disclosed which can be implanted in the human skeleton, and which can act as a scaffold for regrowth of intervertebral disc material. The disc includes a dry, porous, volume matrix of biocompatible and bioresorbable fibers which may be interspersed with glyscosaminoglycan molecules. The matrix is adapted to have in vivo an outer surface contour substantially the same as that of a natural intervertebral disc, whereby said matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of intervertebral fibrochondrocytes. Cross-links may be provided by a portion of the GAG molecules.

Title
Prosthetic intervertebral disc
Application Number
75352
Publication Number
5108438
Application Date
May 7, 1990
Publication Date
April 28, 1992
Inventor
Kevin R Stone
San Francisco
CA, US
Agent
Lahive & Cockfield
Assignee
ReGen Corporation
CA, US
IPC
A61F 2/44
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