05092841 is referenced by 378 patents and cites 17 patents.

A method for treating a lesion in an arterial wall having plaque thereon and a luminal surface, the arterial wall having been mechanically injured during an angioplasty procedure, the arterial wall and the plaque including fissures resulting therefrom, the method comprising the steps of positioning an angioplasty catheter adjacent to the lesion being treated; delivering a bioprotective material between the arterial wall and the angioplasty catheter so that the bioprotective material is entrapped therebetween and permeates into the fissures and small vessels of the arterial wall during apposition of the angioplasty catheter to the arterial wall; applying thermal energy to the lesion, thereby bonding the bioprotective material to the arterial wall and within the fissures; and removing the angioplasty catheter, the bioprotective material remaining adherent to the arterial wall and within the fissures, thereby coating the luminal surface of the arterial wall with an insoluble layer of the bioprotective material so that the insoluble layer provides at least semi-permanent protection to the arterial wall, despite contact with blood flowing adjacent thereto.

Title
Method for treating an arterial wall injured during angioplasty
Application Number
7/525104
Publication Number
5092841
Application Date
May 17, 1990
Publication Date
March 3, 1992
Inventor
James R Spears
Bloomfield Hills
MI, US
Agent
Brooks & Kushman
Assignee
Wayne State University
MI, US
IPC
A61M 29/00
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