05063245 is referenced by 62 patents and cites 1 patents.

The present invention relates to a method of producing corticotropin-releasing factor (CRF) antagonist activity and thus provides a method of treating a wide range of stress-related disorders, including affective illnesses, such as depression and anxiety, as well as irritable bowel syndrome, anorexia nervosa, cardiovascular abnormalities and stress-induced immune suppression. The invention also relates to compounds (4-substituted thio-5-oxo-3-pyrazolines) and to pharmaceutical compositions suitable for use in such a method.

Title
Corticotropin-releasing factor antagonism compounds
Application Number
7/500478
Publication Number
5063245
Application Date
March 28, 1990
Publication Date
November 5, 1991
Inventor
Richard L Elliott
Baltimore
MD, US
Roger N Hiner
Baltimore
MD, US
Donald J Kyle
Baltimore
MD, US
Waclaw Rzeszotarski
Millersville
MD, US
Mary E Abreu
Baltimore
MD, US
Agent
Vincent L Fabiano
Assignee
Nova Pharmaceutical Corporation
MD, US
IPC
C07D 231/22
A61K 31/415
View Original Source