05052388 is referenced by 267 patents and cites 20 patents.

A cardiac pacemaker system of the type including a sensor responsive to the metabolic demand for oxygen and which varies the pacing rate in response to the output of the sensor. The pacemaker defines a function relating sensor output to pacing rate, based upon independently selectable parameters, including a first rate which may be the lower rate of the pacemaker, a second rate which may also be the upper rate of the pacemaker, and a predetermined activity level. The function defined by the pacemaker varies the pacing rate between the first and second rates, with the second rate being achieved at the selected sensor output. The pacemaker system provides both simplicity and extraordinary flexibility, allowing rate responses to be optimized to the needs of a individual patients.

Title
Method and apparatus for implementing activity sensing in a pulse generator
Application Number
7/455717
Publication Number
5052388
Application Date
December 22, 1989
Publication Date
October 1, 1991
Inventor
Robert A Betzold
Fridley
MN, US
Joel E Sivula
White Bear Lake
MN, US
Assignee
Medtronic
MN, US
IPC
A61N 1/365
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