05017375 is referenced by 13 patents and cites 4 patents.

The present invention is based on the discovery that amyotrophic lateral sclerosis (ALS), Parkinson disease and Alzheimer disease are due to lack of a disorder-specific neurotrophic hormone or factor. Diagnosis is accomplished by assaying factors specific for a particular neuronal network or system; for example, dopamine neutotrophic hormones from striatum or caudate-putamen in the nigrostriatal dopaminergic neural system are used to diagnose and treat parkinsonism. With tissue culture, the presence or absence of spacific neurotrophic factos can be assessed in ALS, parkinsonism, and Alzheimer disease. If there is a deficiency, extracted and purified neurotrophic factors specific to the particular neuronal network or system can be injected into a patient having ALS, Alzheimer disease or parkinsonism for treatment of the disease.

Title
Method to prepare a neurotrophic composition
Application Number
444293
Publication Number
5017375
Application Date
May 18, 1987
Publication Date
May 21, 1991
Inventor
Yasuko Tomozawa
Houston
TX, US
Stanley H Appel
Houston
TX, US
Agent
Davis Hoxie Faithfull & Hapgood
Assignee
Baylor College of Medicine
TX, US
IPC
A61K 35/34
A61K 37/02
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