05001054 is referenced by 374 patents and cites 14 patents.

A method for monitoring the glucose level in a body fluid uses an apparatus which includes a conjugate of glucose oxidase and a fluorescent dye coated onto an optical fiber in contact with the body fluid, a source of excitation light and a fluorescence emission detector. Glucose is oxidized by oxygen in the body fluid causing a decrease in oxygen concentration at the enzyme. The fluorescent dye is sensitive to oxygen quenching so that, when the oxygen concentration decreases, fluorescence emission increases in direct proportion to the glucose concentration in the fluid.

Title
Method for monitoring glucose
Application Number
878560
Publication Number
5001054
Application Date
July 31, 1990
Publication Date
March 19, 1991
Inventor
Daniel B Wagner
Raleigh
NC, US
Agent
Richard E Brown
Assignee
Becton Dickinson and Company
NJ, US
IPC
C12M 1/34
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