04970145 is referenced by 423 patents and cites 11 patents.

Enzyme electrodes are disclosed which are capable of responding amperometrically to the catalytic activity of the enzyme in the presence of its respective substrate and comprising the enzyme immobilized or adsorbed onto the surface of an electrically conductive support member which consists of or comprises a porous layer of resin-bonded carbon or graphite particles, said particles having intimately mixed therewith, or deposited or adsorbed onto the surface of the individual particles prior to bonding to form said layer, a finely divided platinum group metal, thereby to form a porous, substrate layer onto which said enzyme is adsorbed or immobilized and comprising a substantially heterogeneous layer of resin-bonded carbon or graphite particles, with said platinum group metal dispersed substantially uniformly throughout said layer. The preferred substrate materials are resin bonded platinized carbon paper electrodes comprising platinized carbon powder particles having colloidal platinum adsorbed on the surface of the particles and bonded onto a carbon paper substrate using a synthetic resin, preferably polytetrafluoroethylene, as the binder. The preferred enzyme electrodes are glucose oxidase electrodes comprising glucose oxidase adsorbed or immobilized onto the surface of the substrate.

Title
Immobilized enzyme electrodes
Application Number
7/146278
Publication Number
4970145
Application Date
January 20, 1988
Publication Date
November 13, 1990
Inventor
David R DeKeyzer
Old Woking
GB
John L Stirling
London
GB
Christopher F Thurston
London
GB
Jeremy R Mason
London
GB
Gerard M Delaney
London
GB
Hugh P Bennetto
London
GB
Agent
St Onge Steward Johnston & Reens
Assignee
Cambridge Life Sciences
GB
IPC
C12N 9/04
C12M 1/40
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