04959217 is referenced by 261 patents and cites 34 patents.

This invention concerns novel, delayed/sustained release devices and compositions, including methods of their manufacture and use. The compositions include macromolecules, particularly polypeptide pharmaceuticals, and an initially partially-hydrated, non-biodegradable, hydrogel rate-limiting membrane.

Title
Delayed/sustained release of macromolecules
Application Number
6/866042
Publication Number
4959217
Application Date
May 22, 1986
Publication Date
September 25, 1990
Inventor
Abraham Domb
Brookline
MA, US
Lynda M Sanders
Palo Alto
CA, US
Agent
John A Dhuey
David A Lowin
Assignee
Syntex
CA, US
IPC
A61K 9/24
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