04956348 is referenced by 8 patents and cites 14 patents.

A method and preparation for the stimulation of tear secretion. The method involves topically applying a phosphodiesterase inhibitor and/or cyclic nucleotide analogue to the ocular surface. Inhibition of phosphodiesterase and cyclic nucleotide analogues increase cyclic nucleotide levels in lacrimal gland tissue, thereby stimulating tear secretion. The preparation contains a phosphodiesterase inhibitor or a cyclic nucleotide analogue and a vehicle for the phosphodiesterase inhibitor or cyclic nucleotide analogue, and may contain an ophthalmic preservative.

Title
Stimulation of tear secretion with cyclic nucleotides
Application Number
830997
Publication Number
4956348
Application Date
June 27, 1988
Publication Date
September 11, 1990
Inventor
Darlene A Dartt
Newton
MA, US
Jeffrey P Gilbard
Boston
MA, US
Agent
Lahive & Cockfield
Assignee
Eye Research Institute of Retina Foundation
MA, US
IPC
A61K 31/70
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