A method and apparatus for automatically testing chemical and ionic sensing electronic circuits is provided. A fluid used in testing is placed in a hollow pipette with at least one open end. The open end of the pipette is applied directly against a sensing layer on the sensing electronic circuit forming a leakproof seal. Alternatively, a flow-through type fluid container is used and is advantageously applied with gas measurements. Test electronics are provided to compile and analyze the performance of various sensing layers. Aligning means automatically select a sensing electronic circuit and position the circuit such that the holding device can be urged against the sensing layer automatically.