04861988 is referenced by 125 patents and cites 5 patents.

A device for interfacing between a microbore liquid chromatograph and a mass analyser. In such a device, liquid from the liquid chromatograph is sprayed through a stainless steel capillary tube into the atmospheric pressure ionization chamber of a mass spectrometer. A voltage of e.g., plus or minus 3 KV is applied to the stainless steel tube, and a nebulizing gas, e.g. nitrogen, is directed at high velocity past the tube tip through another tube encircling the stainless steel tube. The combination of the nebulizing gas and the electric potential disperses the liquid at room temperature into a fine mist providing an increased and more stable ion signal without thermal decomposition of the compounds being analysed.

Title
Ion spray apparatus and method
Application Number
7/103056
Publication Number
4861988
Application Date
September 30, 1987
Publication Date
August 29, 1989
Inventor
Andries P Bruins
Leek
NL
Thomas R Covey
Houston
TX, US
John D Henion
Trumansburg
NY, US
Agent
Laff Whitesel Conte & Saret
Assignee
Cornell Research Foundation
NY, US
IPC
B01D 59/44
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