A contaminant shield prevents airborne contaminants from contacting manufactured parts in a work area in a manufacturing facility. The contaminant shield is formed of a plurality of like frames, each formed of a plurality of interconnected side frame members covered by a flexible sheet attached at its outer edges to the side frame members. The frames are interconnected at adjacent edges to form the complete contaminant shield. A sealing strip is applied to the joints between adjacent frames to form a continuous contaminant barrier in conjunction with the flexible sheet attached to each frame. The contaminant shield is constructed by first constructing a plurality of frames by interconnecting side frame members into a rigid, planar frame and attaching the edges of a flexible sheet to each side frame member of the frame. Each of the side frame members includes an aperture which receives a complimentrally shaped cap which traps the edges of the flexible sheet between itself and the aperture in the side frame for securely attaching the flexible sheet to the side frame.