The present invention relates to an apparatus for applying hemostatic or ligating clips. The apparatus is provided with a unitary chassis on which all other components are attached. A clip housing is disposed at the forward end of the apparatus and stores a plurality of abuttingly arranged forward facing clips that are fed one at a time to the jaws. Upon closure of the handles, the jaws are drawn rearwardly into the apparatus and cammed closed to deform a clip positioned between the jaws. Upon release of the handles, the apparatus returns to its unactuated position and advances a clip to the jaws. The apparatus includes a lockout member to prevent actuation of the apparatus while a clip is in transition from the clip housing to the jaws.