04822566 is referenced by 223 patents and cites 6 patents.

An apparatus for detecting the presence and/or measuring the concentration of an analyte in the fluid medium is disclosed. The apparatus relies on biospecific binding between a biochemical binding system and the analyte to change the dielectric properties of a capacitive affinity sensor. The biological affinity sensor is optimized by: (1) adjusting the thickness and dielectric properties of a passivation layer to generally match the impedance of the biological binding system; and (2) minimize the double layer capacitance so that bulk capacitance changes associated with the biological binding system are maximized.

Title
Optimized capacitive sensor for chemical analysis and measurement
Application Number
799761
Publication Number
4822566
Application Date
May 18, 1987
Publication Date
April 18, 1989
Inventor
Arnold L Newman
Kensington
MD, US
Agent
Howard W Califano
Robert E Archibald
Assignee
The Johns Hopkins University
MD, US
IPC
G01N 27/22
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