04805623 is referenced by 453 patents and cites 21 patents.

A spectrophotometric method is described of quantitatively determining the concentration of a dilute component in either a clear or a strongly light-scattering environment containing same in unknown concentration together with a reference component of known concentration, by a series of contemporaneous radiation-directing and measurement steps of radiation of selected varying wavelengths. Specific applications are disclosed involving the in situ, in vivo, non-invasive spectrophotometric determination of blood-borne as well as tissue species, e.g., hemoglobin, and oxyhemoglobin, and intra-cellular enzyme cytochrome c oxidase, in human body parts such as fingers, hands, toes, feet, earlobes, etc., as well as organs such as the brain, skeletal muscle, liver, etc.

Title
Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment
Application Number
7/93482
Publication Number
4805623
Application Date
September 4, 1987
Publication Date
February 21, 1989
Inventor
Frans F Jobsis
Efland
NC, US
Agent
Steven J Hultquist
Assignee
Vander Corporation
NC, US
IPC
G01N 33/48
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