04712555 is referenced by 336 patents and cites 15 patents.

A pacemaker and physiological sensor for use therewith that allows the rate at which the pacemaker delivers electrical stimulation pulses to the heart, or the escape interval during which a natural heart event must occur before an electrical stimulation pulse is delivered, to be adjusted as needed in order to satisfy the body's physiological needs. The sensor measures the depolarization time interval between an atrial stimulation pulse, A, and the responsive atrial or ventricle depolarization, P or R respectively, as an indication of the physiological demands placed on the heart. The time interval between a ventricular stimulation pulse, V, and the responsive ventricular depolarization, R, may also be measured and used as an indication of physiological need, and hence as an alternative criteria for rate control. Atrial depolarization is sensed by detecting a P-wave, and ventricular depolarization is preferably sensed by detecting an R-wave. A method of measuring A-P, A-R, or V-R intervals is used to ascertain if these intervals are increasing or decreasing. If, over several heart cycles or beats, an increase or decrease in these measurements is detected, the pacing interval set by the pacemaker is adjusted in an appropriate direction in order to adjust the heart stimulation rate accordingly.

Title
Physiologically responsive pacemaker and method of adjusting the pacing interval thereof
Application Number
662723
Publication Number
4712555
Application Date
March 27, 1985
Publication Date
December 15, 1987
Inventor
David C Amundson
Pacific Palisades
CA, US
James R Thacker
Saugus
CA, US
Jason A Sholder
Canoga Park
CA, US
John W Poore
Chatsworth
CA, US
Hans T Thornander
Paris
FR
Agent
Robert R Meads
Bryant R Gold
Assignee
Siemens Elema
SE
IPC
A61N 1/36
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