04695281 is referenced by 15 patents and cites 7 patents.

The medical material according to this invention contains collagen, which as been chemically modified by saccinylation of thermal --NH.sub.2 groups of said chains attached to poly peptide chains of the collagen so that the --NH.sub.2 groups are converted into groups having --COOH groups. This succinylation can be carried out by reacting succinic anhydride with the --NH.sub.2 groups of the collagen. Since the above medical material has excellent compatibility with living bodies, especially, with blood, it is suitable to use it as a replacement material for tissues and/or organs which are kept in contact with blood at their surfaces, namely, is suitable for use in artificial blood vessels, artificial valves, some parts of artificial hearts which are kept in contact with blood at said parts, etc. and as a patching material for hearts.

Title
Medical material
Application Number
6/478773
Publication Number
4695281
Application Date
March 25, 1983
Publication Date
September 22, 1987
Inventor
Yasuharu Noishiki
Tottori
JP
Teruo Miyata
Tokyo
JP
Agent
Armstrong Nikaido Marmelstein & Kubovcik
Assignee
Koken
JP
IPC
A61F 2/06
A61F 2/02
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