04675299 is referenced by 73 patents and cites 13 patents.

A self-contained reagent package device for an assay comprises a support member and a plurality of wells in the support member. All of the wells are capable of retaining liquids therein. At least one of the wells has an aperture at its bottom end for the passage of liquids therethrough. The one well includes a carrier to which a reagent is bound and further includes a porous filter positioned between the carrier and the aperture which is capable of retaining liquids used in the assay under normal atmospheric pressure conditions. The filter permits the passage of those liquids, including unbound and soluble substances, at increased pressure within the one well. Further, the filter is capable of retaining the carrier and substances bound thereto. At least one of the wells includes a predetermined amount of reagent therein. Another of the wells is empty so that the specimen to be assayed may be deposited therein. A removable protective cover is sealed over the open ends of the wells to maintain the incorporated reagents in stable form prior to use. A method for the performance of an assay using the above-described device is another aspect of the present invention.

Title
Self-contained reagent package device and an assay using same
Application Number
6/681034
Publication Number
4675299
Application Date
December 12, 1984
Publication Date
June 23, 1987
Inventor
Roger E Smith
Bountiful
UT, US
Robert E Curry
Ramsey
NJ, US
Thomas R Witty
Salt Lake City
UT, US
Agent
Richard J Rodrick
Assignee
Becton Dickinson and Company
NJ, US
IPC
G01N 21/03
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