An inflatable padded game ball, such as a football, having an outer carcass, a padding inside the carcass, a liner inside the padding and a bladder inside the liner. The liner is so dimensioned relative to the carcass that the liner establishes the final dimensions of the ball when the bladder is inflated within it. The bladder is air impervious and is formed of multiple layers to increase strength and durability. The liner is also formed of multiple layers including inner and outer woven fabric reinforcement layers and a plastic sheet middle layer for establishing the shape of the ball. The method of constructing such a ball includes a mold of smaller dimensions than the final dimensions of the ball which molds the shape of the inner liner. When the ball is removed from the mold the carcass and padding expand to the final size of the ball.