04659825 is referenced by 29 patents and cites 4 patents.

This invention relates to isomeric O-phosphonylmethyl derivatives of the formula I ##STR1## wherein R.sup.5 designates an adenin-9-yl moiety, R.sup.4 are alternately a hydrogen atom and a --CH.sub.2 P(O)(OH).sub.2 group, and the configuration at the carbon atom in the position 2 is S, R or RS.

The compounds according to the invention are biologically active as inhibitors of metabolic processes and in organism they are stable towards enzymes, cleaving phosphomonoester bonds.

The said compounds exhibit also chemosterilizing action on insects.

Title
Isomeric O-phosphonylmethyl derivatives of enantiomeric and racemic 9-(2,3-dihydroxypropyl)adenine
Application Number
6/568719
Publication Number
4659825
Application Date
January 6, 1984
Publication Date
April 21, 1987
Inventor
Karel Slama
Prague
CS
Ivan Rosenberg
Prague
CS
Antonin Holy
Prague
CS
Agent
Leydig Voit & Mayer
Assignee
Ceskoslovenska akademie
CS
IPC
C07H 19/16
C07F 9/65
C07F 9/38
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