04652441 is referenced by 258 patents and cites 9 patents.

A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.

Title
Prolonged release microcapsule and its production
Application Number
6/667096
Publication Number
4652441
Application Date
November 1, 1984
Publication Date
March 24, 1987
Inventor
Takatsuka Yashiki
Takarazuka
JP
Yasuaki Ogawa
Ibaraki
JP
Hiroaki Okada
Suita
JP
Agent
Wegner & Bretschneider
Assignee
Takeda Chemical
JP
IPC
B01J 13/02
A61K 9/52
View Original Source