04642120 is referenced by 294 patents and cites 1 patents.

There are provided compositions for repairing defects of cartilage and bones. These are provided in gel form either as such, or embedded in natural or artificial bones. The gel comprises certain types of cells. These may be committed embryonal chondocytes or any kind of mesenchyme originated cells which potentially can be converted to cartilage cells, generally by the influence of chondrogenic inducing factors, in combination with fibrinogen, antiprotease and thrombin. The cells ought to be of the species to which the composition is transplanted. It is advantageous to incorporate in the gel extracellular matrix (ECM) of chondrocytes or other hormones and/or growth factors such as SM (Somatomedin=IGF-I), FGF (fibroblast growth factor), CGF (cartilage growth factor), BDGF (bone derived growth factor) or a combination of any of these.

Title
Repair of cartilage and bones
Application Number
6/591822
Publication Number
4642120
Application Date
March 21, 1984
Publication Date
February 10, 1987
Inventor
Samuel Itay
Kfar Saba
IL
Zvi Nevo
Herzlia
IL
Agent
Fleit Jacobson Cohn & Price
Assignee
Ramot University Authority for Applied Research and Industrial Development
IL
IPC
A61F 2/02
A61F 2/28
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