04599353 is referenced by 242 patents.

Ocular hypertension and glaucoma can be effectively controlled in primates through topical application of an effective amount of an eicosanoid or an eicosanoid derivative to the surface of an afflicted eye. Eicosanoids, particularly the prostaglandins PGE.sub.2 and PGF.sub.2.alpha., and derivatives thereof, have been found effective in quantities less than about 1000 .mu.g per eye. Ophthalmic compositions containing C.sub.1 to C.sub.5 alkyl esters of PGF.sub.2.alpha. are presently preferred for use in treating ocular hypertension and glaucoma in primates, including man.

Title
Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
Application Number
6/374165
Publication Number
4599353
Application Date
May 3, 1982
Publication Date
July 8, 1986
Inventor
Laszlo Z Bito
New York
NY, US
Agent
John P White
Assignee
The Trustees of Columbia University in the City of New York
NY, US
IPC
A61K 31/215
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