04596795 is referenced by 136 patents and cites 7 patents.

The administration of sex hormones, particularly testosteorne, progesterone and estradiol in the form of their complexes or inclusions with specific derivatives of cyclodextrins by the sublingual or buccal route results in effective transfer of these hormones into the systemic circulation, followed by only gradual elimination. To be effective in the above mode of administration, the derivatives of cyclodextrins must carry one or several substituents, each containing one or several hydroxy groups. Specially preferred are the following complexes: hydroxypropylbeta-cyclodextrin and poly-beta-cyclodextrin.

Title
Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
Application Number
6/603839
Publication Number
4596795
Application Date
April 25, 1984
Publication Date
June 24, 1986
Inventor
Josef Pitha
Baltimore
MD, US
Agent
John S Roberts Jr
Assignee
The United States of America represented by the Secretary Dept of Health & Human Services
DC, US
IPC
A61K 31/70
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