04582640 is referenced by 271 patents and cites 4 patents.

Cross-linked atelopeptide collagen that is substantially free of residual cross-linking agent is prepared by: reconstituting atelopeptide collagen from solution by neutralizing the solution at a reduced temperature and a hypotonic ionic strength; cross-linking the reconstituted fibers in an aqueous medium at a concentration of 0.1 to 10 mg/ml with glutaraldehyde under conditions that produce cross-linked collagen that when in suspension in physiological saline at a concentration of 35 mg/ml exhibits a shear viscosity whose log varies linearly with the log of the shear rate and is approximated by the formula

Title
Injectable cross-linked collagen implant material
Application Number
355879
Publication Number
4582640
Application Date
October 22, 1984
Publication Date
April 15, 1986
Inventor
Donald G Wallace
Menlo Park
CA, US
John McPherson
Sunnyvale
CA, US
Thomas L Smestad
Palo Alto
CA, US
Agent
Ciotti & Murashige
Assignee
Collagen Corporation
CA, US
IPC
A61L 15/04
C08L 89/06
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