04455256 is referenced by 176 patents and cites 5 patents.

Bone morphogenetic protein (BMP) made by the process comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone collagen to gelatin and extracting BMP into the solution of solubilizing agent; and separating the solubilizing agent and neutral salt from the solution, thereby precipitating BMP in the aqueous medium, and the BMP has a molecular weight in the range of 1,000-100,000.

Title
Bone morphogenetic protein
Application Number
6/260726
Publication Number
4455256
Application Date
May 5, 1981
Publication Date
June 19, 1984
Inventor
Marshall R Urist
Pacific Palisades
CA, US
Agent
Kenyon & Kenyon
Assignee
The Regents of the University of California
CA, US
IPC
C07G 7/00
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