04453939 is referenced by 170 patents and cites 4 patents.

A composition and its use for sealing and healing of wounds, comprising a collagen carrier which is coated on one face or all faces with a mixture of (1) a fibrinogen component which contains fibrinogen, factor XIII-containing fibrinogen or a mixture thereof, and (2) a thrombin component which contains thrombin, a substance which liberates thrombin in the presence of body fluid or a mixture of such substances. The mixture of (1) and (2) optionally may additionally contain conventional additives, such as calcium ions, protease inhibitors, heparin antagonists, substances which promote the infiltration and growth of fibroblasts, such as fibronectin, as well as antibiotics and/or bactericides.

Title
Composition for sealing and healing wounds
Application Number
6/347817
Publication Number
4453939
Application Date
February 11, 1982
Publication Date
June 12, 1984
Inventor
Ulrich Schiele
Munich
DE
Eberhard Zimmerman
Munster
DE
Agent
Mark Dryer
Assignee
Hormon Chemie Munchen
DE
IPC
A61K 37/02
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