04450171 is referenced by 119 patents and cites 14 patents.

6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H- pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.

Title
Antihypercholesterolemic compounds
Application Number
118051
Publication Number
4450171
Application Date
June 14, 1982
Publication Date
May 22, 1984
Inventor
Alvin K Willard
Wilmington
DE, US
Robert L Smith
Lansdale
PA, US
William F Hoffman
Lansdale
PA, US
Agent
Mario A Monaco
William H Nicholson
Assignee
Merck & Co
NJ, US
IPC
C07D 309/30
A61K 31/335
C07C 69/74
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