04450150 is referenced by 302 patents and cites 6 patents.

An implantable drug deliver depot comprising a hydrophilic poly(glutamic acid-co-ethyl glutamate) structure having one or more substances, e.g., drugs and/or diagnostic agents physically contained therein. The drug or diagnostic agent is released by its permeation of and diffusion through the copolymer structure. The depot may be designed to release the substance or substances at predetermined rates and in predetermined sequence. The copolymer structure ultimately biodegrades to glutamic acid. Among the preferred configurations for the depots are rods and closed-end capsules.

Title
Biodegradable, implantable drug delivery depots, and method for preparing and using the same
Application Number
361182
Publication Number
4450150
Application Date
May 11, 1981
Publication Date
May 22, 1984
Inventor
Kenneth R Sidman
Wayland
MA, US
Agent
Richard J Hammond
Assignee
Arthur D Little
MA, US
IPC
A61K 9/06
A61K 37/24
A61K 43/00
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