04438052 is referenced by 88 patents and cites 7 patents.

A process for producing bilayer vesicles from a colloidal solution comprising mixed micelles of a bilayer-forming substance and a detergent, comprises removing the detergent from the micelle-containing colloidal solution by means of flow-through dialysis whereby the colloidal solution is dialyzed against a dialysis liquid in a chamber whose walls are at least partially formed by a semi-permeable membrane, wherein the dialysis liquid is moved along the outer side of the semi-permeable membrane at a velocity such that the detergent concentration in the dialysis liquid, on at least 90% of the active surface of the membrane, is at most 10% of the detergent concentration in the micelle solution in contact with the other side of the membrane, and wherein a homogeneous detergent concentration is maintained in the micelle solution by the movement of the latter.

Title
Process and device for producing bilayer vesicles
Application Number
6/224993
Publication Number
4438052
Application Date
January 14, 1981
Publication Date
March 20, 1984
Inventor
Manfred Milsmann
Bielefeld
DE
Reto Schwendener
Arosa
CH
Otmar Zumbuhl
Wolfenshiessen
CH
Hans G Weder
E. Merck, Postfach 4119, 6100 Darmstadt 1
DE
Agent
Millen & White
Assignee
Hans Georg Weder
CH
IPC
B01D 13/00
B01J 13/02
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