04431004 is referenced by 740 patents and cites 4 patents.

A method and apparatus for more accurate measurements of the glucose content in body fuids by sensing the absolute level of oxygen concentration in the fluid and correcting the output differential measurement indicative of the glucose content in the fluid according to the absolute level of oxygen.

In the two electrode systems known to the art, the unaltered oxygen electrode of the electrode pair may be employed to read the absolute level of oxygen concentration and in addition, function to establish the difference in oxygen concentration caused by glucose oxidation.

In view of the fact that temperature may vary, a thermistor may be included in the electrode system to make temperature corrections for reason that the absolute oxygen reading from either a polarographic or galvanic oxygen electrode is extremely sensitive to temperature and the rate of glucose oxidation is temperature sensitive.

Title
Implantable glucose sensor
Application Number
6/315282
Publication Number
4431004
Application Date
October 27, 1981
Publication Date
February 14, 1984
Inventor
Lyell J Thomas
1900 Pelican Ave., San Pedro, 90732
CA, US
Ennis C Layne
9128 Huntington Dr., San Gabriel, 91775
CA, US
Samuel P Bessman
2025 Zonal Ave., Los Angeles, 90033
CA, US
Agent
Fidelman Wolffe & Waldron
IPC
A61B 5/00
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