04407943 is referenced by 114 patents and cites 9 patents.

An antigen or antibody and an immunochemically neutral protein are immobilized in two stages on a microporous membrane coated with a protein such as zein or collagen. Immobilized antigen to Toxoplasma gondii is used in an immunoassay to detect the presence of antibody to Toxoplasma gondii in serum. Antibody that becomes bound to the immobilized antigen is detected with an antibody- enzyme conjugate. Immobilizing the immunochemically netural protein on the membrane in a second stage immobilization step minimizes nonspecific binding during the immunoassay.

Title
Immobilized antibody or antigen for immunoassay
Application Number
751099
Publication Number
4407943
Application Date
March 13, 1980
Publication Date
October 4, 1983
Inventor
Deborah M Van Voorhis
Watertown
MA, US
Francis X Cole
Stow
MA, US
Agent
Paul J Cook
David Prashker
Assignee
Millipore Corporation
MA, US
IPC
C12N 11/02
C12Q 1/04
G01N 33/54
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