04402940 is referenced by 61 patents and cites 2 patents.

This invention provides a method for treating blood plasma wherein a hollow fiber membrane which comprises at least a skin layer on one surface of the membrane and also a porous layer inside the membrane is employed. The skin layer of the membrane has micropores with average pore size of 50 to 450 A, and the membrane shows a water permeability of 80 ml/m.sup.2.hr.mmHg or more, and permeabilites for human blood plasma albumin of 85% or more and for human blood plasma immunoglobulin G(IgG) of 80% or more, and a rate of inhibition against human blood plasma immunoglobulin M(IgM) of 40% or more. Use of the above mentioned hollow fiber membrane, which makes it possible to selectively remove immune complex, rheumatoid factors, etc., without decrease in levels of immunological functions, brings excellent effects on therapy of autoimmune diseases.

Title
Method for treating blood plasma employing a hollow fiber membrane
Application Number
6/418551
Publication Number
4402940
Application Date
September 17, 1982
Publication Date
September 6, 1983
Inventor
Paul S Malchesky
Painesvilla Township, Lake County
OH, US
Andrej Werynski
Warsaw
PL
James Smith
Cleveland
OH, US
Shigeru Shinagawa
Cleveland
OH, US
Yoshihiro Asanuma
Sendai
JP
Akinori Sueoka
South Euclid
OH, US
Koji Kayashima
Mayfield
OH, US
Yukihiko Nose
Cleveland
OH, US
Agent
Barry Kramer
Assignee
Kuraray
JP
IPC
A61K 35/14
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