04389393 is referenced by 313 patents and cites 11 patents.

A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being one or more hydroxypropylmethylcelluloses or a mixture of one or more hydroxypropylmethylcelluloses and up to 30% by weight of the mixture of methylcellulose, sodium carboxymethylcellulose and/or other cellulose ether, and wherein at least one of the hydroxypropylmethylcelluloses has a methoxy content of 16-24 weight-%, a hydroxypropoxyl content of 4-32 weight-% and a number average molecular weight of at least 50,000 and wherein the carrier base material constitutes less than about one third of the weight of the solid unit dosage form.

Title
Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
Application Number
6/362104
Publication Number
4389393
Application Date
March 26, 1982
Publication Date
June 21, 1983
Inventor
Norman G Gaylord
New Providence
NJ, US
Ashok Nigalaye
Jackson Heights
NY, US
Joseph M Schor
Locust Valley
NY, US
Agent
Jacobs & Jacobs
Assignee
Forest Laboratories
NY, US
IPC
A61K 9/26
A61K 9/22
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