04344438 is referenced by 534 patents and cites 7 patents.

A system for monitoring low molecular weight compounds in blood plasma in the body by optical means includes a chamber which can be inserted into the blood stream and which contains specific receptor sites for the plasma constituent to be analyzed. The chamber interior is isolated from the blood by a dialysis membrane which permits the plasma constituents to diffuse into the chamber. A competing ligand for the receptor sites is placed within the chamber, but due to its relatively large molecular size the competing ligand cannot escape through the dialysis membrane into the bloodstream. Light emitted or absorbed by the competing ligand gives a measure of the concentration of the selected low molecular weight compounds in the blood.

Title
Optical sensor of plasma constituents
Application Number
930659
Publication Number
4344438
Application Date
April 28, 1980
Publication Date
August 17, 1982
Inventor
Jerome S Schultz
Ann Arbor
MI, US
Agent
Browdy and Neimark
Assignee
The United States of America represented by the Department of Health Education and Welfare
DC, US
IPC
A61B 5/00
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