04343788 is referenced by 67 patents and cites 28 patents.

The present invention relates to medical polymers and devices made therefrom, and is based on the discovery that certain carboxylate antimicrobial agents can be releasably incorporated into permeable polymers. The walls of medical devices such as catheters can be fashioned from such polymers. In use, the antimicrobial agent diffuses from the walls to the surface of the device to form an antimicrobial barrier on the surface of the device and a zone of microbial inhibition on tissue surfaces surrounding the device, thereby effectively supplementing the body's own natural microbial barriers where they have been compromised. The bacterial contamination-resistant carboxylate-plus-polymer compositions herein can be used in the manufacture of a wide variety of medical devices, especially urinary catheters, intravenous catheters, wound dressings, and the like.

Title
Antimicrobial polymer compositions
Application Number
6/53619
Publication Number
4343788
Application Date
June 29, 1979
Publication Date
August 10, 1982
Inventor
Roger L Stone
Fairfield
OH, US
Donald S Lucas
Fairfield
OH, US
Robert V Mustacich
Fairfield
OH, US
Agent
Richard C Witte
Steven J Goldstein
Michael J Roth
Assignee
The Procter & Gamble Company
OH, US
IPC
A61K 31/74
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