04294753 is referenced by 251 patents and cites 4 patents.

The process of separating bone morphogenetic protein (BMP) from bone tissue comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone collagen to gelatin and extracting BMP into the solution of solubilizing agent; and separating the solubilizing agent and neutral salt from the solution, thereby precipitating BMP in the aqueous medium.

Title
Bone morphogenetic protein process
Application Number
6/174906
Publication Number
4294753
Application Date
August 4, 1980
Publication Date
October 13, 1981
Inventor
Marshall R Urist
Pacific Palisade
CA, US
Agent
Kenyon & Kenyon
Assignee
The Regents of the University of California
CA, US
IPC
C07G 7/00
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