04291024 is referenced by 46 patents and cites 2 patents.

Nucleotides of nucleosides or bases having known cytotoxic activity are reacted to form corresponding cytotoxic liponucleotide analogs by phosphorylation of molecular species of phosphatidic acids. The resulting cytotoxic liponucleotide analogs exhibit an enhanced therapeutic index and broader spectrum of antitumor activity as compared to the parent nucleoside or base compounds, apparently due to an improved selective uptake thereof by metabolizing tumor cells, and are thus useful cytotoxic, antiviral and antineoplastic agents.

Title
Cytotoxic liponucleotide analogs
Application Number
895231
Publication Number
4291024
Application Date
January 18, 1980
Publication Date
September 22, 1981
Inventor
Joseph G Turcotte
30 Greenwood Dr, Peace Dale, 02879
RI, US
Agent
Haight Rosfeld & Noble
IPC
C07H 19/20
C07H 19/10
A61K 31/70
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