04289690 is referenced by 115 patents and cites 28 patents.

An improved process for purifying proteins, particularly proteins having molecular weights in excess of 12,000 involves novel applications of high performance liquid chromatography on a preparative scale to provide homogeneous end product in excellent yield. In an embodiment of the process, human interferon is produced as a homogeneous protein.

Title
Protein purification process and product
Application Number
963257
Publication Number
4289690
Application Date
July 9, 1980
Publication Date
September 15, 1981
Inventor
Menachem Rubinstein
Rimon
IL
Sidney Pestka
North Caldwell
NJ, US
Agent
Peter R Shearer
George M Gould
Jon S Saxe
Assignee
Hoffmann La Roche
NJ, US
IPC
C07C 103/52
A61K 45/02
C07G 7/00
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