04249531 is referenced by 117 patents and cites 14 patents.

A device for the controlled continuous administration of an active agent to an environment of use is disclosed. The device comprises a body of erodible agent release rate controlling material containing an agent dispersed therethrough; the rate controlling material is a hydrophobic poly(carboxylic acid) having one ionizable carboxylic hydrogen for each 8 to 12 carbon atoms, which material erodes at a controlled and continuous rate over a prolonged period of time in response to the environment by a process of carboxylic hydrogen ionization, thereby releasing the dispersed agent at a controlled rate over a prolonged period of time.

Title
Bioerodible system for delivering drug manufactured from poly(carboxylic acid)
Application Number
318831
Publication Number
4249531
Application Date
July 5, 1979
Publication Date
February 10, 1981
Inventor
Richard W Baker
Bend
OR, US
Jorge Heller
Palo Alto
CA, US
Agent
Edward L Mandell
Thomas E Ciotti
Paul L Sabatine
Assignee
Alza Corporation
CA, US
IPC
A61M 7/00
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