04245634 is referenced by 413 patents and cites 5 patents.

An artificial beta cell regulates blood glucose concentration in a subject by continuously analyzing blood from the patient and deriving a computer output signal to drive a pump which infuses insulin at a rate corresponding to the signal. A value of blood glucose concentration from the analyzed blood is used by a computer to determine a rate of change of this concentration which in turn is used to derive a projected blood glucose level. A sigmoidal relationship between the projected blood glucose concentration and the rate of infusion is used to determine the actual rate of infusion required and hence an output signal is fed to the pump to create this actual rate of insulin infusion.

Title
Artificial beta cell
Application Number
639948
Publication Number
4245634
Application Date
February 12, 1979
Publication Date
January 20, 1981
Inventor
Bernard S Leibel
Newmarket
CA
Anthony M Albisser
Toronto
CA
Agent
Hirons Rogers & Scott
Assignee
Hospital for Sick Children
CA
IPC
A61J 7/00
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